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BioMed Research International
Volume 2013 (2013), Article ID 585134, 7 pages
Association of Apolipoprotein A5 Gene 1131TC Polymorphism with the Risk of Metabolic Syndrome in Korean Subjects
Division of Constitutional Medicine Research, and Herbal Medicine Research Division, Korea Institute of Oriental Medicine (KIOM), 483 Expo-ro, Yuseong-gu, Daejeon 305-811, Republic of Korea
Received 20 August 2012; Accepted 26 December 2012
Academic Editor: M. Ilyas Kamboh
Copyright © 2013 Kwang Hoon Song et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- R. H. Eckel, S. M. Grundy, and P. Z. Zimmet, “The metabolic syndrome,” The Lancet, vol. 365, no. 9468, pp. 1415–1428, 2005.
- E. Expert Panel on Detection, and Treatment of High Blood Cholesterol in Adults, “Executive summary of the third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III),” The Journal of the American Medical Association, vol. 285, no. 19, pp. 2486–2497, 2001.
- S. Lim, H. Shin, J. H. Song, et al., “Increasing prevalence of metabolic syndrome in Korea: the Korean national health and nutrition examination survey for 1998–2007,” Diabetes Care, vol. 34, no. 6, pp. 1323–1328.
- L. Groop, “Genetics of the metabolic syndrome,” British Journal of Nutrition, vol. 83, supplement 1, pp. S39–S48, 2000.
- T. Joy and R. A. Hegele, “Genetics of metabolic syndrome: is there a role for phenomics?” Current Atherosclerosis Reports, vol. 10, no. 3, pp. 201–208, 2008.
- C. M. Povel, J. M. Boer, E. Reiling, et al., “Genetic variants and the metabolic syndrome: a systematic review,” Obesity Reviews, vol. 12, no. 11, pp. 952–967, 2011.
- A. H. Kissebah, G. E. Sonnenberg, J. Myklebust et al., “Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome,” Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 26, pp. 14478–14483, 2000.
- S. Francke, M. Manraj, C. Lacquemant et al., “A genome-wide scan for coronary heart disease suggests in Indo-Mauritians a susceptibility locus on chromosome 16p13 and replicates linkage with the metabolic syndrome on 3q27,” Human Molecular Genetics, vol. 10, no. 24, pp. 2751–2765, 2001.
- C. D. Langefeld, L. E. Wagenknecht, J. I. Rotter et al., “Linkage of the metabolic syndrome to 1q23-q31 in hispanic families: the insulin resistance atherosclerosis study family study,” Diabetes, vol. 53, no. 4, pp. 1170–1174, 2004.
- A. T. Kraja, D. Vaidya, J. S. Pankow et al., “A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium,” Diabetes, vol. 60, no. 4, pp. 1329–1339, 2011.
- L. A. Pennacchio, M. Olivier, J. A. Hubacek et al., “An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing,” Science, vol. 294, no. 5540, pp. 169–173, 2001.
- P. J. Talmud, E. Hawe, S. Martin et al., “Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides,” Human Molecular Genetics, vol. 11, no. 24, pp. 3039–3046, 2002.
- J. T. Kao, H. C. Wen, K. L. Chien, H. C. Hsu, and S. W. Lin, “A novel genetic variant in the apolipoprotein A5 gene is associated with hypertriglyceridemia,” Human Molecular Genetics, vol. 12, no. 19, pp. 2533–2539, 2003.
- T. Nabika, S. Nasreen, S. Kobayashi, and J. Masuda, “The genetic effect of the apoprotein AV gene on the serum triglyceride level in Japanese,” Atherosclerosis, vol. 165, no. 2, pp. 201–204, 2002.
- L. Baum, B. Tomlinson, and G. N. Thomas, “APOA5-1131T>C polymorphism is associated with triglyceride levels in Chinese men,” Clinical Genetics, vol. 63, no. 5, pp. 377–379, 2003.
- B. E. Aouizerat, M. Kulkarni, D. Heilbron et al., “Genetic analysis of a polymorphism in the human apoA-V gene: effect on plasma lipids,” Journal of Lipid Research, vol. 44, no. 6, pp. 1167–1173, 2003.
- T. Zhao and J. Zhao, “Association of the apolipoprotein A5 gene −1131T>C polymorphism with fasting blood lipids: a meta-analysis in 37859 subjects,” BMC Medical Genetics, vol. 11, no. 1, article 120, 2010.
- A. Maasz, P. Kisfali, K. Horvatovich, et al., “Apolipoprotein A5 T-1131C variant confers risk for metabolic syndrome,” Pathology and Oncology Research, vol. 13, no. 3, pp. 243–247, 2007.
- Y. Yamada, K. Kato, T. Hibino et al., “Prediction of genetic risk for metabolic syndrome,” Atherosclerosis, vol. 191, no. 2, pp. 298–304, 2007.
- L. A. Hsu, Y. L. Ko, C. J. Chang, et al., “Apolipoprotein A5 gene -1131T/C polymorphism is associated with the risk of metabolic syndrome in ethnic Chinese in Taiwan,” Clinical Chemistry and Laboratory Medicine, vol. 46, no. 12, pp. 1714–1719, 2008.
- H. Grallert, E. M. Sedlmeier, C. Huth, et al., “APOA5 variants and metabolic syndrome in Caucasians,” Journal of Lipid Research, vol. 48, no. 12, pp. 2614–2621, 2007.
- E. Komurcu-Bayrak, A. Onat, M. Poda et al., “Gender-modulated impact of apolipoprotein A5 gene (APOA5) −1131T>C and c.56C>G polymorphisms on lipids, dyslipidemia and metabolic syndrome in Turkish adults,” Clinical Chemistry and Laboratory Medicine, vol. 46, no. 6, pp. 778–784, 2008.
- K. H. Song, S. G. Yu, S. Cha, and J. Y. Kim, “Association of the apolipoprotein A5 gene −1131T>C polymorphism with serum lipids in Korean subjects: impact of Sasang constitution,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 598394, 8 pages, 2012.
- S. Jeong, H. Yu, Y. Lee, and J. Y. Kim, “SNP genotyping through the melting analysis of unlabelled oligonucleotide applied on dilute PCR amplicon,” Journal of Biotechnology, vol. 154, no. 4, pp. 321–325, 2011.
- A. D. Association, “Diagnosis and classification of diabetes mellitus,” Diabetes Care, vol. 29, supplement 1, pp. S43–S48, 2006.
- WHO/IASO/IOTF, The Asia-Pacific Perspective: Redefining Obesity and Its Treatment, Health Communications, Melbourne, Australia, 2000.
- C. Q. Jiang, T. H. Lam, B. Liu et al., “Interleukin-6 receptor gene polymorphism modulates interleukin-6 levels and the metabolic syndrome: GBCS-CVD,” Obesity, vol. 18, no. 10, pp. 1969–1974, 2010.
- N. Sarwar, M. S. Sandhu, S. L. Ricketts et al., “Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies,” The Lancet, vol. 375, no. 9726, pp. 1634–1639, 2010.
- C. P. Oliva, F. Carubbi, F. G. Schaap, S. Bertolini, and S. Calandra, “Hypertriglyceridaemia and low plasma HDL in a patient with apolipoprotein A-V deficiency due to a novel mutation in the APOA5 gene,” Journal of Internal Medicine, vol. 263, no. 4, pp. 450–458, 2008.
- Y. Jang, J. Y. Kim, O. Y. Kim et al., “The -1131T→C polymorphism in the apolipoprotein A5 gene is associated with postprandial hypertriacylglycerolemia; elevated small, dense LDL concentrations; and oxidative stress in nonobese Korean men,” American Journal of Clinical Nutrition, vol. 80, no. 4, pp. 832–840, 2004.
- K. H. Lee, O. Y. Kim, H. H. Lim, Y. J. Lee, Y. Jang, and J. H. Lee, “Contribution of APOA5-1131C allele to the increased susceptibility of diabetes mellitus in association with higher triglyceride in Korean women,” Metabolism, vol. 59, no. 11, pp. 1583–1590, 2010.