The Variety of Vertebrate Mechanisms of Sex Determination

Figure 2

The role AMH in repressing of Müllerian duck differentiation. The Wolffian duck has to be maintained and stimulated to differentiate into the male tract and accessory organ. Then, the Müllerian duct system has to regress, due to action AMH secreted by Sertoli cells. Sox9 and Sf1 are both involved in the expression of the AMH gene as a result of their respective binding to the promoter and in part because of their ability to interact with each other (adopted from [17]).