Effects of Naked Gold Nanoparticles on Proinflammatory Cytokines mRNA Expression in Rat Liver and Kidney

Table 1

Commercial properties of GNPs and the rat doses used in this study.

Commercial preparation			Effective dosage/animal/day*			Shape**
GNP	Size	Number of particles (concentration)	Volume	Au	Number of GNPs
MKN-Au-010	10 nm	5.7 × 10^12/mL; (0.01% Au/mL)	50 μL	5 μg	2.85 × 10^11
MKN-Au-050	50 nm	4.5 × 10^10/mL; (0.01% Au/mL)	50 μL	5 μg	2.25 × 10^9

∗This dose is approximately equivalent to 22 μg/kg bodyweight of rat. **TEM images showing that the shape of 10 nm GNP is spherical and that of 50 nm GNP is hexagonal.