Table 2: Regions of cerebral activations during painful stimulation of the ET-1 injected arm.

LobusGyrusSideTalairachBA lowest P value
x y z

Noxious mechanical stimulation
Frontal lobeIpsilateral6032465.9
Frontal lobeContralateral−2−46064.20.00005
Frontal lobeContralateral−50−34168.9
Frontal lobeContralateral−16463685.8
Frontal lobeContralateral−11563096.80.000000209
Frontal lobeIpsilateral50418465.60.000002
Frontal lobeContralateral−413416466.20.0000000228
Frontal lobeContralateral−44222477
Frontal lobeIpsilateral58913446.40.0000000228
Frontal lobeContralateral−511194411.7
Frontal lobeIpsilateral9523093.90.00068
Frontal lobeIpsilateral5165282.90.0039
Parietal lobeContralateral−54−253829.6
Parietal lobeIpsilateral50−4343404.30.000064
Parietal lobeContralateral−45−26204013.5
Parietal lobeIpsilateral49−6132395.40.000001
Parietal lobeIpsilateral55−213026.10.00000015
Temporal lobeContralateral−65−275227.3
Temporal lobeIpsilateral45−614376.8
Temporal lobeContralateral−46−653377.8
Temporal lobeContralateral−49−6224397.9
Temporal lobeIpsilateral67−326227.1
Occipital lobeIpsilateral34−899192.90.0094
Occipital lobeContralateral−35−897193.50.003
Occipital lobeContralateral−27−85−7183.90.00034
Occipital lobeIpsilateral33−891183.60.00035
AmygdalaContralateral−27−2−105.10.000005
Limbic lobeIpsilateral16−39−8303.40.0093
Limbic lobeIpsilateral5−645244.10.000082
Limbic lobeContralateral−12−347243.10.0011
InsulaIpsilateral44−3521138
InsulaContralateral−46−26201313.3