Research Article

Biochemical, Pharmacological, and Structural Characterization of New Basic Bbil-TX from Bothriopsis bilineata Snake Venom

Figure 6

(a, b) Time course of the increments in plasma CK activity after intramuscular (i.m.) or intravenous (i.v.) injection of 0.1, 1, and 5 μg Bothriopsis bilineata Bbil-TX; (c) in vitro cytotoxic activity of Bbil-TX on murine C2C12 skeletal-muscle myoblasts and myotubes. Cell lysis was estimated by the release of lactic dehydrogenase (LDH) to supernatants, after 3 h of exposure to the toxins. Each point represents of triplicate cell cultures.
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