The Impact of Aspergillus fumigatus Viability and Sensitization to Its Allergens on the Murine Allergic Asthma Phenotype
Figure 6
Effect of inhaled dead or live A. fumigatus conidia on systemic and mucosal antibody levels in a sensitized murine host. Total IgE (a, b), IgA (c, d), IgG1 (e, f), and IgG2a (g, h) levels were determined in the serum (a, c, e, and g) and BALF (b, d, f, and h) samples obtained from mice challenged with dead or live A. fumigatus conidia, at days 3, 7, and 28 after third fungal challenge. Commercially available mouse-specific ELISAs were used for this purpose. Bars represent mean ± SEM, mice/group. *, #, value < 0.05, as compared with naïve mice or mice challenged with dead conidia, respectively.
