Table 2: The impact of haplotype reconstruction method on the variability parameters of HVR1.

Correction methodI
Cut-off 1%
II
Bidirectional coverage
III
ShoRAH

Number of haplotypes840186
Number of nucleotide substitutions within HVR1515970
Percentage of mutated amino acid positions within HVR1 (%)55.655.674.1
Genetic distance3.8740.0650.110
Genetic diversity0.9230.9980.984