Table 2: The current available radiopharmaceuticals for radioimmunotherapy of lymphoma.

-Zevalin 131I-Bexxar 131I-Rituximab

Radioisotope   
(   =  2.67 days)
131I  
(   =  8.01 days)
131I  
(   =  8.01 days)
Anti-CD20 antibodyIbritumomab tiuxetanTositumomabRituximab
Antibody typeMonoclonal murineMonoclonal murineMonoclonal chimeric
Predose injectionUnlabeled rituximabUnlabeled tositumomabUnlabeled rituximab
Pretherapy imagingYes (for biodistribution)Yes (for dosimetry)Yes (for dosimetry)
Pretherapy dose111In-Zevalin (5 mCi) 131I-Bexxar (5 mCi) 131I-Rituximab (5 mCi)
Treatment dose0.4 mCi/kg (up to 32 mCi)75 cGy (whole body)75 cGy (whole body)