Table 1: Effect of 5-LO deficiency on pentobarbital (50 mg/kg, i.p.)-induced sleeping time in mice.

GroupsSleeping time (min)

WT142.8 ± 10.10
5-LO−/−128.25 ± 7.25

Data as mean ± S.E.M.; per group, versus WT (Student’s -test).