|Table 1: Evaluation of the mutagenicity of the S9 fraction that was obtained from rats that were treated with biotin in the Ames test.|
|The mean number of revertant colonies identified in three replicates in two independent experiments.|
(b)The liver S9 fraction from control rats.
(c)The liver S9 fraction from biotin-treated rats (2 mg/kg).
(d)The liver S9 fraction from phenobarbital-treated rats (60 mg/kg). -naphthoflavone (80 mg/kg) was used as a positive control.
(e)The slope at the origin was calculated using the SALANAL software program.
*Significantly different from B− and B+ (), as assessed using Student’s -test.