Protective Efficacy of N-(2-Hydroxyphenyl) Acetamide against Adjuvant-Induced Arthritis in Rats

<table>Effect of NA-2 on serum levels of IL-1<i>β</i> in arthritic and nonarthritic animals. A significant increase (*<svg height="11.375" id="M141" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) in the levels of serum IL-1<i>β</i> was found in the arthritic control group compared to normal animals. In contrast to the arthritic control group, both the indomethacin and NA-2 treatments were observed to decrease the IL-1<i>β</i> in the serum of the treated animals (<svg height="13.95" id="M142" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 73.300003 13.95" width="73.300003" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) which was comparable to that of the normal control group.</table>

BioMed Research International

fig2

Figure 2

Figure 2: Protective Efficacy of N-(2-Hydroxyphenyl) Acetamide against Adjuvant-Induced Arthritis in Rats 