Impact of Genetic Variants of Apolipoprotein E on Lipid Profile in Patients with Parkinson's Disease

Table 1

Distribution of absolute and relative frequencies of alleles and genotypes of APOE polymorphism in individuals with Parkinson's disease (PD) and without (Controls).

Genotype; APOE	PD (𝑁=232)		Controls (𝑁=137)		𝑃^∗
	N	%	N	%
Genotype
APOE2/4	1	0.4	0	—	—
APOE2/3	19	8.1	8	5.8	0.535
APOE3/3	169	73.0	103	75.2	0.713
APOE3/4	37	15.9	24	17.5	0.772
APOE4/4	6	2.6	2	1.5	0.727
Total	232	100	137	100
APOE-/4	44	18.9	26	18.9	1.000
APOE-/2	20	8.6	8	5.8	0.413
Allele
APOE2	20	0.04	8	0.03	0.426
APOE3	394	0.85	238	0.87	0.515
APOE4	50	0.11	28	0.10	0.901
Total	464	1.0	274	1.0

∗Fisher or Chi-squared tests; N: total number of individuals; Abs. Freq.: absolute frequency.