Immune Modulation and Stereotactic Radiation: Improving Local and Abscopal Responses
Figure 1
Stereotactic radiosurgery versus conventional radiation. Left three images depict stereotactic radiosurgery for a lung tumor: (a) shows a patient’s transverse CT image through the lung tumor (red = tumor outline, purple = everything inside the line is receiving at least 100% of the full prescribed radiation dose, yellow = everything inside the line is receiving at least 60% of the full prescribed radiation dose, and green = everything inside the line is receiving at least 30% of the full prescribed radiation dose); (c) shows the same patient in coronal CT view; and (e) shows the 11 beams of radiation centered on the tumor, to generate a radiation plan that is highly focused on the tumor. Right three images depict a more traditional radiation plan for a lung tumor (colored lines defined same as images on the left): (b) shows a patient’s transverse CT image through the lung tumor; (d) shows the same patient in coronal CT view; and (f) shows the 2 beams of radiation centered on the tumor. In comparison to conventional radiation, stereotactic radiosurgery is able to focus the high and medium radiation dose regions around the tumor while sparing normal tissues and organs.
