Immune Modulation and Stereotactic Radiation: Improving Local and Abscopal Responses

Figure 2

Proton radiation dose distribution. Patient with a tumor in the pituitary gland, receiving proton radiation to the tumor (innermost cyan shaded area). Upper three images show the radiation dose distribution from a photon radiation treatment plan using multiple converging beams on axial CT image (left upper), sagittal CT image (middle upper), and coronal CT image (right upper). Lower three images show the radiation dose distribution from a proton radiation treatment plan using three proton beams on axial CT image (left lower), sagittal CT image (middle lower), and coronal CT image (right lower). For all images, innermost red line = everything inside the line is receiving at least 100% of the full prescribed radiation dose, and outermost blue line = everything inside the line is receiving at least 20% of the full prescribed radiation dose. Note that the high radiation dose region (inside the red line) looks similar between the photon and proton plan, but the lower radiation dose region (inside the blue line) is much smaller with proton radiation than photon radiation.