Research Article

Antimicrobial Activity, Growth Inhibition of Human Tumour Cell Lines, and Phytochemical Characterization of the Hydromethanolic Extract Obtained from Sapindus saponaria L. Aerial Parts

Table 3

Cytotoxicity of hydromethanolic extract of Sapindus saponaria aerial parts and ellipticine (standard) in human tumor cell lines and in nontumor liver primary culture.

Extract (GI50, μg/mL)Ellipticine (GI50, μg/mL)

HCT-15 (colon carcinoma)
HepG2 (hepatocellular carcinoma)>800
HeLa (cervical carcinoma)
MCF-7 (breast carcinoma)
NCI-H460 (lung carcinoma)

PLP2 (nontumor liver cells)>800

GI50 values correspond to the sample concentration achieving 50% of growth inhibition in human tumor cell lines or in liver primary culture PLP2.