Combined Treatment with Low Concentrations of Decitabine and SAHA Causes Cell Death in Leukemic Cell Lines but Not in Normal Peripheral Blood Lymphocytes

<table>Effect of DAC and/or SAHA on cell viability during 48-hour treatment. Cells of leukemic cell lines CML-T1 (a, circles) and HL-60 (b, squares) or PBL (c, triangles) were treated by 1 <i>μ</i>M DAC (full line), 1 <i>μ</i>M SAHA (dash line), or 1 <i>μ</i>M DAC + 1 <i>μ</i>M SAHA (dotted line) in the 48 h time frame, and then their metabolic activity was measured by MTT test. Data are the average of at least five experiments and ±SEM are plotted as error bars.</table>

BioMed Research International

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Figure 1

Figure 1: Combined Treatment with Low Concentrations of Decitabine and SAHA Causes Cell Death in Leukemic Cell Lines but Not in Normal Peripheral Blood Lymphocytes 

Figure 1 | Combined Treatment with Low Concentrations of Decitabine and SAHA Causes Cell Death in Leukemic Cell Lines but Not in Normal Peripheral Blood Lymphocytes 