Magnetic Resonance Imaging of Cardiovascular Fibrosis and Inflammation: From Clinical Practice to Animal Studies and Back
Figure 5
Contrast-enhanced 7 T MRT images of the aorta from ApoE-deficient rats. Three different groups (fat-rich diet with ezetimibe during 8 months (a), fat-rich diet during 8 months and ezetimibe the last 4 months (b), and fat-rich diet without ezetimibe during 8 months (c)) were studied at 4, 6, and 8 months and compared with histology at 8 months. The aortic wall thickness increased with a fat-rich diet, whereas this effect was inhibited with ezetimibe (modified from doctoral dissertation of Dr. Weyers, Charité Faculty of Medicine, Berlin; unpublished data).
