Rapid Identification of Aldose Reductase Inhibitory Compounds from Perilla frutescens

Table 3

Inhibitory effects of compounds 1–6 isolated from EtOAc-soluble fractions of P. frutescens extract on rAR.

Number	Compound	IC50 (μM)^a
1	Protocatechuic acid	—
2	Chlorogenic acid	3.16
3	Caffeic acid	—
4	Rosmarinic acid	2.77
5	Luteolin	6.34
6	Methyl rosmarinic acid	4.03
	Quercetin^b	5.07

aThe IC₅₀ value was defined as the concentration at 50% inhibition.
^bQuercetin, positive control.