Research Article

Hyaluronic Acid Derived from Other Streptococci Supports Streptococcus pneumoniae In Vitro Biofilm Formation

Figure 2

Effect of hyaluronic acid (HA) on pneumococcal biofilm growth. Time course experiment in YE medium (blue bars) or YE medium supplied with either 0.2% glucose (red bars) or hyaluronic acid (black bar). The biomass of biofilm were detected by crystal-violet microtiter plate assay. The significance of the results ( ) between biomass of biofilm grown in positive control ( ), hyaluronic acid ( ), and negative control (YE only) was determined by one-way analysis of variance (ANOVA). The error bars represent the standard deviations (SD).
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