Role of the Plasma Membrane Transporter of Organic Cations OCT1 and Its Genetic Variants in Modern Liver Pharmacology

Table 1

Xenobiotic compounds transported by human OCT1.

Category	Compounds	References
Alkaloids	APD-ajmalinium	[10]
	Berberine	[58]
	Nicotine	[59]
Fluorescent dyes	4′,6-diamidino-2-phenylindole (DAPI)	[60]
	4-(4-(dimethylamino)-styryl)-N-methylpyridinium (ASP)	[56, 61]
	[2-(4-nitro-2,1,3-benzoxadiazole-7-yl)aminoethyl]trimethylammonium	[62]
	Ethidium	[63]
Herbicides	Paraquat	[64]
Neurotoxins	1-Methyl-4-phenylpyridinium (MPP^+)	[50]
	1-Methyl-4-phenyl-tetrahydropyridine (MPTP)	[38]
Quaternary ammonium compounds	Tetraalkylammonium	[10]
Uremic toxins	Guanidinosuccinic acid	[65]
	Methylguanidine
	Guanidinovaleric acid
Mycotoxins	Aflatoxin B1	[66]