Antioxidant and Hepatoprotective Effect of Aqueous Extract of Germinated and Fermented Mung Bean on Ethanol-Mediated Liver Damage
Table 1
Effect of mung bean extracts on serum ALT, AST, TG, and cholesterol in alcohol-induced acute liver toxicity in mice.
Treatment
ALT (U/L)
AST (U/L)
TG (mmol/L)
Cholesterol (mmol/L)
Normal untreated
14.09 ± 1.53
98.16 ± 1.99
1.48 ± 0.23
3.14 ± 0.39
50% EtOH (placebo)
48.11 ± 1.78
367.30 ± 1.10
2.37 ± 0.14
3.80 ± 0.20
50% EtOH + silybin (50 mg/kg)
26.72 ± 1.20*
171.70 ± 3.79*
2.77 ± 0.16
4.20 ± 0.36
50% EtOH + mung bean (200 mg/kg)
63.44 ± 2.73*
294.50 ± 6.28*
2.06 ± 0.22*
3.28 ± 0.31*
50% EtOH + mung bean (1000 mg/kg)
28.09 ± 1.32*
234.19 ± 6.87*
2.05 ± 0.44*
3.29 ± 0.41*
50% EtOH + germinated mung bean (200 mg/kg)
57.57 ± 3.60*
308.61 ± 1.33*
2.21 ± 0.06*
3.40 ± 0.01*
50% EtOH + germinated mung bean (1000 mg/kg)
26.34 ± 3.50*
191.93 ± 1.51*
1.84 ± 0.35*
3.13 ± 0.06*
50% EtOH + fermented mung bean (200 mg/kg)
56.26 ± 4.71*
232.48 ± 1.52*
2.26 ± 0.12*
3.18 ± 0.21*
50% EtOH + fermented mung bean (1000 mg/kg)
17.45 ± 1.88*
110.77 ± 6.96*
1.46 ± 0.76*
2.91 ± 0.19*
Values are mean ± SEM of 8 animals each in a group and significantly different from the 50% EtOH (Placebo) (*) by ANOVA and followed by Duncan's multiple range test.
