Antioxidant and Hepatoprotective Effect of Aqueous Extract of Germinated and Fermented Mung Bean on Ethanol-Mediated Liver Damage
Table 2
Effect of mung bean extracts on SOD, MDA, FRAP, and NO levels in liver homogenate of alcohol-induced acute liver toxicity in mice.
Treatment
SOD (U/mg of protein)
MDA (nmol/g of protein)
FRAP (U/mg of protein)
NO (mol/mg of protein)
Normal untreated
16.58 ± 0.58*
3.02 ± 0.16*
9.40 ± 1.04*
9.97 ± 0.25*
50% EtOH (placebo)
9.17 ± 0.79
7.17 ± 0.17
5.33 ± 0.04
14.72 ± 0.75
50% EtOH + silybin (50 mg/kg)
17.06 ± 0.01*
4.92 ± 0.20*
14.97 ± 0.08*
9.39 ± 2.70*
50% EtOH + mung bean (200 mg/kg)
16.48 ± 2.72*
3.74 ± 0.25*
8.82 ± 0.25*
11.04 ± 0.39*
50% EtOH + mung bean (1000 mg/kg)
17.07 ± 3.77*
3.78 ± 0.33*
5.63 ± 0.01
10.29 ± 0.11*
50% EtOH + germinated mung bean (200 mg/kg)
16.64 ± 0.73*
2.54 ± 0.20*
9.83 ± 0.02*
9.54 ± 0.04*
50% EtOH + germinated mung bean (1000 mg/kg)
17.11 ± 1.26*
2.31 ± 0.26*
5.74 ± 0.02
8.84 ± 0.42*
50% EtOH + fermented mung bean (200 mg/kg)
18.00 ± 0.34*
3.22 ± 0.32*
5.52 ± 0.02
10.78 ± 0.03*
50% EtOH + fermented mung bean (1000 mg/kg)
21.35 ± 0.44*
2.00 ± 0.23*
11.92 ± 0.03*
9.03 ± 0.06*
Values are mean ± SEM of 8 animals each in a group and significantly different from the 50% EtOH (placebo) (*) by ANOVA and followed by Duncan's multiple range test.
