How Ocular Surface Disease Impacts the Glaucoma Treatment Outcome

Table 1

Topical glaucoma medications: systemic and ocular side effects.

	Systemic side effects	Ocular side effects
Nonselective beta-blockers	Decreased heart rate, bradycardia, arrhythmias, exacerbation of heart failure, masking of hypoglycemic symptoms, and depression	Burning, redness, decreased ocular blood flow, and decreased corneal sensation
Alpha-2 agonists	Hypotension, respiratory depression (in infants), central nervous system depression (in infants), sedation, and fatigue	Redness, itching, pupillary dilatation, and lid retraction
Carbonic anhydrase inhibitors	Allergy, bitter taste, and low blood counts	Stinging, irritation, and red eyes
Prostaglandin analogs	No significant side effects	Hyperemia, changes in particularly skin pigmentation, changes in iris color, and eye-lash growth

Table information adapted from [7, 8].