In Silico Screening and Molecular Dynamics Simulation of Disease-Associated nsSNP in TYRP1 Gene and Its Structural Consequences in OCA3

Figure 4

Time evolution of the secondary structural elements of the native and mutant (R326H and R356Q) Tyrp1 proteins at 300 K (DSSP classification). (a) Native, (b) mutant R326H, and (c) mutant R356Q.

(a)

(b)

(c)