Table 4: Average values of RMSD, Rg, SASA, NH-bonds, trace of co-variance, and density value of native and mutant (R326H and R356Q) structures.

NativeMutant (R326H)Mutant (R356Q)

RMSD0.620.500.52
Rg1.841.811.79
SASA74.571.269.1
NH-bonds84.793.292.4
Density value41.952.252.3
Trace of Co-variance11.5610.748.16

RMSD: root-mean-square deviation; Rg: radius of gyration; SASA: solvent accessible surface area; NH bonds: number of hydrogen bonds. The value of RMSD, Rg and SASA, co-variance, and total helicity are given in nm, whereas density value is given in nm−3.