Research Article
Embryotoxic and Teratogenic Effects of Nickel in Swiss Albino Mice during Organogenetic Period
Table 4
Fetuses with skeleton anomalies after maternal exposure to Ni+2 (as NiCl2·6H2O).
| | Parameters (%) | Group I
(control) | Group II
(46.125 mg Ni/kg b.wt.) | Group III
(92.25 mg Ni/kg b.wt.) | Group IV
(184.5 mg Ni/kg b.wt.) |
| | Total fetuses with different skeletal anomalies | 0 | 22.7 | 35.0 | 50.0 | | Skull | 0 | 18.1 | 25.0 | 40.6 | | Vertebral column | 0 | 0 | 5.0 | 9.3 | | Ribs | 0 | 4.5 | 5.0 | 6.2 | | Sternum | 0 | 9.0 | 15.0 | 18.7 | | Pelvic elements | 0 | 0 | 5.0 | 6.2 | | Caudal vertebrae | 0 | 0 | 5.0 | 6.2 | | Carpals, metacarpals, tarsals, metatarsals, and phalanges | 0 | 18.1 | 25.0 | 46.8 |
|
|
