HLA-B*40 Allele Plays a Role in the Development of Acute Leukemia in Mexican Population: A Case-Control Study

Table 3

Gene frequencies of HLA-B alleles in patients with AML compared with umbilical cord blood samples, as a control group.

B* allele	Patients 𝑁=85		Controls 𝑁=731		𝑃	OR	95% CI
	𝑛	g. f.	𝑛	g. f.
07	11	0.0647	60	0.0410	NS
08	5	0.0294	40	0.0273	NS
13	3	0.0176	14	0.0095	NS
14	7	0.0411	55	0.0376	NS
15	2	0.0117	135	0.0923	0.0001	0.11	0.02–0.45
18	6	0.0352	42	0.0287	NS
27	9	0.0529	19	0.0129	0.0001	4.44	1.79–10.8
35	30	0.1764	296	0.2024	NS
37	3	0.0176	6	0.0041	NS
38	2	0.0117	15	0.0102	NS
39	23	0.1352	254	0.1737	NS
40	8	0.0470	144	0.0984	0.02	0.42	0.18–0.93
41	3	0.0176	13	0.0088	NS
44	11	0.0647	75	0.0512	NS
45	3	0.0176	18	0.0123	NS
48	5	0.0294	57	0.0389	NS
49	5	0.0294	29	0.0198	NS
50	2	0.0117	11	0.0075	NS
51	16	0.0941	86	0.0588	NS
52	7	0.0411	40	0.0273	NS
53	3	0.0176	17	0.0116	NS
55	1	0.0058	2	0.0013	NS
57	3	0.0176	15	0.0102	NS
58	2	0.0117	6	0.0041	NS

AML: acute myeloid leukemia; g. f.: gene frequency; OR: odds ratio; CI: confidence interval; NS: not significant.