Table 1: Advantages and disadvantages of vectors for iPS.

AdvantageDisadvantageEfficiency

Nonintegrating vectorNonintegratingLow efficiency, need for multiple rounds of transfection0.001%
EpisomalNonintegrating, single round of transfectionLow efficiency, labour intensive0.001%
MinicircleNonintegrating, higher transfection efficiencyPotentially cytotoxic0.005%