Distal Airway Impairment in Obese Normoreactive Women
Table 1
Lung function data of the BMI-normal, overweight, and obese patients, in the entire population.
Variables
Total
BMI < 25
25 ≤ BMI < 30
BMI ≥ 30
value
Smoking
0.2350
Yes
39 (13.31)
29 (15.93)
8 (12.90)
2 (4.08)
No
228 (77.82)
137 (75.27)
50 (80.65)
41 (83.67)
Former smoker
26 (8.87)
16 (8.76)
4 (6.45)
6 (12.24)
Age (years)
41.04 (12.80)
37.91 (12.76)
45.38 (12.39)***
47.18 (9.32)**
<0.0001
BMI (kg/m2)
24.65 (5.41)
21.22 (2.19)
27.45 (1.51)***
33.83 (4.02)***
<0.0001
FVC (L)
3.20 (0.59)
3.36 (0.54)
2.99 (0.61)**
2.89 (0.56)***
<0.0001
FVC (% pred)
0.99 (0.14)
1.01 (0.14)
0.97 (0.13)
0.98 (0.15)
0.1094
FEV1 (L)
2.72 (0.54)
2.88 (0.52)
2.49 (0.49)**
2.42 (0.48)**
<0.0001
FEV1 (% pred)
0.98 (0.14)
0.99 (0.14)
0.94 (0.13)*
0.97 (0.16)
0.0287
FEV1/FVC (%)
0.85 (0.06)
0.86 (0.07)
0.84 (0.05)*
0.84 (0.05)*
0.0375
FVC fall (%)
11.32 (8.71)
10.66 (8.84)
10.85 (8.07)
14.37 (8.53)**
0.0111
FEV1 fall (%)
16.92 (9.96)
16.72 (10.38)
15.17 (9.40)
19.86 (8.53)*
0.0230
FVC DRS
0.03 (0.10)
0.03 (0.11)
0.02 (0.03)
0.05 (0.11)**
0.0008
FEV1 DRS
0.04 (0.13)
0.04 (0.15)
0.03 (0.05)
0.07 (0.15)**
0.0008
CI
0.68 (0.57)
0.67 (0.64)
0.72 (0.53)
0.71 (0.28)
0.1142
Data are presented as median (interquartile range) (all but smoking) and (%) (smoking). BMI: body mass index; FEV1: forced expiratory volume in one second; FVC: forced volume capacity; DRS: dose-response slope; CI: closing index.
*
versus BMI < 25; ** versus BMI < 25; *** versus BMI < 25.