Immunocytochemical Characterization of Alzheimer Disease Hallmarks in APP/PS1 Transgenic Mice Treated with a New Anti-Amyloid-β Vaccine

Figure 5

Aβ plaque quantification. The density quantification diagram of Aβ burden observed in the hippocampal and cortical regions of APP/PS1 mice in the three treatment groups at the end of preventive and therapeutic periods. The mean of the Aβ burden (plaques/section) is reduced in group A when compared with groups B and C during both treatment periods and decreased in density from preventive to therapeutic in group A, markedly different to that observed in groups B and C.