Formulation Development and Stability Studies of Norfloxacin Extended-Release Matrix Tablets

Table 3

Assay results of accelerated stability test.

Formulation	Time zero		After 6 months
			Blister		Without blister
	Uncoated (%)	Coated (%)	Uncoated (%)	Coated (%)	Uncoated (%)	Coated (%)
HPMC K100LV 20%	101.98	101.09	101.16	101.51	102.03	101.18
HPMC K100LV 30%	101.47	101.81	101.87	103.01	100.87	101.74
HPMC K4M 20%	101.45	100.42	100.44	102.98	101.92	101.08
HPMC K4M 30%	100.88	99.31	99.12	99.45	99.91	98.09
PEO N60K 20%	102.06	101.72	102.89	98.47	101.44	100.26
PEO N60K 30%	99.43	99.92	98.49	99.05	99.44	99.03
PEO 301 20%	99.48	99.35	101.24	97.51	101.75	100.31
PEO 301 30%	99.71	100.50	99.03	100.49	100.61	100.36