CXCR1/CXCR2 Antagonism Is Effective in Pulmonary Defense against Klebsiella pneumoniae Infection

Figure 3

Impact of G31P, dexamethasone, or ceftazidime treatments on inflammatory pathology in guinea pigs with Klebsiella pneumoniae. Guinea-pigs were challenged with Klebsiella pneumonia, treated with G31P, dexamethasone, or ceftazamine, and then sacrificed 24 h later. Each of these treatments markedly reduced the expression levels of both mediators relative to the saline-treated animals. Each experiment was repeated three times; the data depicted are representative of each group.