Table 3: The distribution of PTPN22 C1858T polymorphism in patients with T1DM according to studied parameters.

AlleleGenotype
CTCCCTTTCT + TT
Frequency (%)

Gender
 (male/female) (73/57)136/109 (93.2/95.8)10/5 (6.8/4.4)64/52 (87.7/91.2)8/5 (11.0/8.8)1/0 (1.4/0)9/5
(12.3/8.8)
0.4360.6130.580
Age at onset
( 10/ 10 years) (88/42)166/79 (94.3/94)10/5
(5.7/6)
79/37 (89.8/88.1)8/5 (9.1/11.9)1/0 (1.1/0)9/5 (10.2/11.9)
1.0000.7010.769
Tanner stage at diagnosis
(I/II–V) (99/31)188/57 (94.9/91.9)10/5 (5.1/8.1)90/26 (90.9/83.9)8/5 (8.1/16.1)1/0 (1.0/0)9/5
(9.1/16.1)
0.3610.3730.320
Ketoacidosis at onset
(+/−) (104/26)195/50 (93.8/96.2)13/2 (6.3/3.8)92/24 (88.5/92.3)11/2 (10.6/7.7)1/0 (1.0/0)12/2 (11.5/7.7)
0.7420.7960.735
HT
(+/−) (27/103)49/196 (90.7/95.1)5/10 (9.3/4.9)23/93 (85.2/90.3)3/10 (11.1/9.7)1/0 (3.7/0)4/10 (14.8/9.7)
0.2060.1410.488
Familiar history of T1DM
(+/−) (19/111)37/208 (97.4/93.7)1/14
(2.1/6.3)
18/98 (94.78/88.3)1/12 (5.3/10.8)0/1 (0/0.9)1/13 (5.3/11.7)
0.7040.6890.692