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BioMed Research International
Volume 2013 (2013), Article ID 723780, 10 pages
http://dx.doi.org/10.1155/2013/723780
Research Article

Prediction of Effective Drug Combinations by Chemical Interaction, Protein Interaction and Target Enrichment of KEGG Pathways

1Institute of Systems Biology, Shanghai University, Shanghai 200444, China
2College of Information Engineering, Shanghai Maritime University, Shanghai 201306, China
3Key Laboratory of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
4State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai 201203, China
5Department of Ophthalmology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080, China
6Beijing Genomics Institute, Shenzhen Beishan Industrial Zone, Shenzhen 518083, China

Received 8 June 2013; Accepted 24 July 2013

Academic Editor: Tao Huang

Copyright © 2013 Lei Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The Supplementary Material contains four files. In details, Supplementary Material I lists 726 drug compounds investigated in this study; Supplementary Material II lists the targets of 169 drugs; Supplementary Material III lists the results obtained by mRMR method; Supplementary Material IV lists the accuracies obtained by IFS and random forest.

  1. Supplementary Material I
  2. Supplementary Material II
  3. Supplementary Material III
  4. Supplementary Material IV