About this Journal Submit a Manuscript Table of Contents
BioMed Research International
Volume 2013 (2013), Article ID 724896, 8 pages
http://dx.doi.org/10.1155/2013/724896
Research Article

Establishment of a Lentiviral Vector Encoding Human HGF and the Infection of Human ADSCs

1Department of Hematology, Anhui Provincial Hospital of Anhui Medical University, Hefei 23001, China
2Department of Osteology, Anhui Provincial Hospital of Anhui Medical University, Hefei 23001, China

Received 11 October 2012; Revised 10 December 2012; Accepted 11 December 2012

Academic Editor: Irma Virant-Klun

Copyright © 2012 Xiaoyu Zhu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. X. Y. Zhu, X. Z. Zhang, L. Xu, X. Y. Zhong, Q. Ding, and Y. X. Chen, “Transplantation of adipose-derived stem cells overexpressing hHGF into cardiac tissue,” Biochemical and Biophysical Research Communications, vol. 379, no. 4, pp. 1084–1090, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. T. Tang, J. Yang, F. Li et al., “Experimental study of the effects of marrow mesenchymal stem cells transfected with hypoxia-inducible factor-1 Gene,” Journal of Biomedicine and Biotechnology, vol. 2009, Article ID 128627, 10 pages, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. M. L. Tong, M. Martina, D. W. Hutmacher, J. H. P. O. Hui, H. L. Eng, and B. Lim, “Identification of common pathways mediating differentiation of bone marrow- and adipose tissue-derived human mesenchymal stem cells into three mesenchymal lineages,” Stem Cells, vol. 25, no. 3, pp. 750–760, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. J. K. Fraser, I. Wulur, Z. Alfonso, and M. H. Hedrick, “Fat tissue: an underappreciated source of stem cells for biotechnology,” Trends in Biotechnology, vol. 24, no. 4, pp. 150–154, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. C.-S. Lin, Z.-C. Xin, C.-H. Deng, H. Ning, G. Lin, and T. F. Lue, “Defining adipose tissue-derived stem cells in tissue and in culture,” Histology and Histopathology, vol. 25, no. 6, pp. 807–815, 2010.
  6. J.-H. Kim, M. Jung, H.-S. Kim, Y.-M. Kim, and E.-H. Choi, “Adipose-derived stem cells as a new therapeutic modality for ageing skin,” Experimental Dermatology, vol. 20, no. 5, pp. 383–387, 2011. View at Publisher · View at Google Scholar
  7. J. Shang, K. Deguchi, Y. Ohta et al., “Strong neurogenesis, angiogenesis, synaptogenesis, and antifibrosis of hepatocyte growth factor in rats brain after transient middle cerebral artery occlusion,” Journal of Neuroscience Research, vol. 89, no. 1, pp. 86–95, 2011. View at Publisher · View at Google Scholar
  8. H. Ueda, T. Nakamura, K. Matsumoto, Y. Sawa, H. Matsuda, and T. Nakamura, “A potential cardioprotective role of hepatocyte growth factor in myocardial infarction in rats,” Cardiovascular Research, vol. 51, no. 1, pp. 41–50, 2001. View at Publisher · View at Google Scholar · View at Scopus
  9. K. Kitta, R. M. Day, T. Ikeda, and Y. J. Suzuki, “Hepatocyte growth factor protects cardiac myocytes against oxidative stress-induced apoptosis,” Free Radical Biology and Medicine, vol. 31, no. 7, pp. 902–910, 2001. View at Publisher · View at Google Scholar · View at Scopus
  10. Q.-Y. Yuan, J. Huang, B.-C. Chu, X.-J. Li, X.-S. Li, and L.-Y. Si, “A targeted high-efficiency angiogenesis strategy as therapy for myocardial infarction,” Life Sciences, vol. 90, no. 17-18, pp. 695–702, 2012. View at Publisher · View at Google Scholar
  11. H. M. Sung, I. S. Suh, H.-B. Lee, K. S. Tak, K. M. Moon, and M. S. Jung, “Case reports of adipose-derived stem cell therapy for nasal skin necrosis after filler injection,” Archives of Plastic Surgery, vol. 39, no. 1, pp. 51–54, 2012. View at Publisher · View at Google Scholar
  12. A. Siltanen, K. Kitabayashi, P. Lakkisto et al., “HHGF overexpression in myoblast sheets enhances their angiogenic potential in rat chronic heart failure,” PLoS ONE, vol. 6, no. 4, Article ID e19161, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. T. Sakuma, M. A. Barry, and Y. Ikeda, “Lentiviral vectors: basic to translational,” Biochemical Journal, vol. 443, no. 3, pp. 603–618, 2012. View at Publisher · View at Google Scholar