Ubiquitin Ligase Cbl-b Is Involved in Icotinib (BPI-2009H)-Induced Apoptosis and G1 Phase Arrest of EGFR Mutation-Positive Non-Small-Cell Lung Cancer

Figure 6

Icotinib upregulated expression of Cbl-b. Cells were exposed to 0.01–1 μmol/L icotinib for 24 h, and expression of Cbl-b proteins was analyzed by Western blotting. β-Actin was used as the internal control.