Table 2: Inhibitory effects of compounds isolated from the kernel of Zea mays L. on rat lens aldose reductase (RLAR).

Compounds Concentration (μg/mL) Inhibition (%)IC50
(μg/mL)(μM)

Protochatechuic acid (1)103.22>10
Vanillic acid (2)1020.34>10
2,4,6-trihydroxybenzoic acid (3) 1073.73
548.145.9234.82
116.95
p-hydroxycinnamic acid (4) 1077.81
543.736.0236.71
113.76
Ferulic acid (5)1077.25
549.834.2421.85
111.15
Hirsutrin (6)1086.69
576.152.224.78
127.56
3′-methoxyhirsutrin (7)1089.74
573.672.715.67
116.43
Cyanidin-3-glucoside (8)4047.72>40
Pelargonidin-3-glucoside (9)4013.21>40
Peonidin-3-glucoside (10)4036.98>40
Cyanidin-3-(6′′-malonylglucoside) (11)1067.96
547.786.2711.74
119.01
Pelargonidin-3-(6′′-malonylglucoside) (12)10NAb>10
Quercetina 1082.99
567.912.346.92
130.34

Inhibition rate was calculated as percentage with respect to the control value and expressed as mean of triplicate experiments. The concentration of each test sample giving rise to 50% inhibition of activity (IC50) was estimated from the least-squares regression line of the logarithmic concentration plotted against inhibitory activity. aQuercetin was used as positive control. bNA means nonactive.