Antibodies against Food Antigens in Patients with Autistic Spectrum Disorders

Table 2

This table is a summary of the results; it reports about all the investigated parameters in all subjects. Number of altered values and % are reported for each investigated parameter.

	ASD: number (%)		Controls: number (%)
Recruited	162		44
Positive for celiac disease (tTg > 9 U/mL, EMA positive)	2		0
Enrolled	160 (M 131; F 31)		44 (M 27; F 17)
HLA DQ2/DQ8 (for details see Table 1)	66 (41.0)		Not determined
Total IgA altered (see age based normal range in Supplementary Material available online at http://dx.doi.org/10.1155/2013/729349)	Deficit: 2 (1.3)		Deficit: 0
	Increase: 13 (8.1)		Increase: 3 (6.8)
Total IgG altered (see age based normal range in Supplementary Material)	0		0
Diet regimen: RD: regular diet = no diet restrictions; GF/CF: gluten/casein free diet	RD; (𝑁=129)	GF/CF; (𝑁=31)	Controls RD; (𝑁=44)
LA/MA altered, >0.030	33 (25.6)	8 (25.8)	1 (2.3)
AGA IgA altered, >15 U/mL	3 (2.3)	0	0
AGA IgG altered, >50 U/mL	33 (25.6)	3 (9.7)	4 (9.1)
DPG IgA altered, >5.5 U/mL	3 (2.3)	0	0
DPG IgG altered, >10 U/mL	12 (9.3)	2 (6.5)	0
Total IgE altered (see age based normal range in Supplementary Material)	20 (15.5)	7 (22.6)	4 (9.1)
𝛽-Lactoglobulin IgE > 0.35 kUA/L	12 (9.3)	1 (3.2)	2 (4.6)
𝛼-Lactalbumin IgE > 0.35 kUA/L	16 (12.4)	3 (9.7)	1 (2.3)
Gluten IgE > 0.35 kUA/L	8 (6.2)	0	2 (4.6)
Casein IgE > 0.35 kUA/L	8 (6.2)	0	0
Milk IgE > 0.35 kUA/L	23 (17.8)	3 (9.7)	2 (4.6)
𝛽-Lactoglobulin IgG > 12 mgA/L	30 (23.3)	4 (12.9)	11 (25.0)
𝛼-Lactalbumin IgG > 12 mgA/L	27 (20.9)	3 (9.7)	11 (25.0)
Total gliadin IgG (𝛼,𝛽,𝛾,𝜔) > 12 mgA/L	48 (37.2)	7 (22.6)	10 (22.7)
Casein IgG > 12 mgA/L	45 (34.9)	5 (16.1)	19 (43.2)