Cryobiopsy: Should This Be Used in Place of Endobronchial Forceps Biopsies?

Table 1

Patient diagnosis (𝑛=22) according to biopsy type, location of lesion, biopsy material volume (cm³) corresponding to each biopsy modality, and type of lesion (exophytic or flat).

Cryobiopsy diagnosis	Forceps diagnosis	Location of lesion	Vol. (cm^3) cryobiopsy	Vol. (cm^3) forceps	Type of lesion
Squamous cell carcinoma	Squamous cell carcinoma	BI	0.4	0.2	Exophytic
Benign inflammation	Benign inflammation	RUL	0.06	0.018	Flat
Necroinflammation	Necroinflammation	RUL	0.048	0.001	Flat
Necroinflammation	Necroinflammation	Carina	0.018	0.002	Flat
Papillary squamous cell carcinoma	Papillary squamous cell carcinoma	RMS	0.702	0.004	Exophytic
Adenocarcinoma	Adenocarcinoma	RMS	0.02	0.00025	Exophytic
Adenosquamous	Adenosquamous	RLL	0.004	0.004	Flat
Squamous cell carcinoma	Squamous cell carcinoma	RUL	0.032	0.144	Exophytic
Small cell	Small cell	LMS	0.027	0.021	Exophytic
Benign	Benign	RMS	0.018	0.009	Flat
Squamous cell carcinoma	Squamous cell carcinoma	LLL	0.112	0.006	Exophytic
Poorly differentiated NSCLC	Poorly differentiated NSCLC	LLL	0.024	0.04	Exophytic
Small cell	Small cell	RUL	0.03	0.016	Exophytic
Squamous cell carcinoma	Squamous cell carcinoma	RMS	0.96	0.009	Exophytic
Adenocarcinoma	Adenocarcinoma	LLL	0.045	0.032	Flat
Carcinoid	Carcinoid	RLL	0.39	0.234	Exophytic
Adenocarcinoma	Adenocarcinoma	RLL	0.024	0.006	Flat
Benign	Benign	LUL	0.05	0.032	Flat
Squamous cell carcinoma	Squamous cell carcinoma	RMS	0.042	0.006	Flat
Squamous cell carcinoma	Squamous cell carcinoma	RUL	0.04	0.001	Flat
Squamous cell carcinoma	Squamous cell carcinoma	LMS	0.016	0.003	Flat
Adenocarcinoma	Atypical	RMS	12.25	0.032	Exophytic

NSCLC: Nonsmall cell lung cancer; BI: bronchus intermedius; RUL: right upper lobe; RLL: right lower lobe; LUL: left upper lobe; LLL: left lower lobe; RMS: right main stem; LMS: left main stem.