Review Article

Tight Junction Proteins and Oxidative Stress in Heavy Metals-Induced Nephrotoxicity

Figure 1

Renal distribution of claudins, occludin, and zonula occludens (ZO-1 and ZO-2) along the nephron. Proteins of tight junctions (TJs) display combined expression patterns along the nephron. G: glomerulus; PT: proximal tubule; DTL: descending thin limb of Henle; ATL: ascending thin limb of Henle; TAL: thick loop of Henle; DT: distal tubule; CD: collecting duct.
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