Altered Functional Connectivity within and between Brain Modules in Absence Epilepsy: A Resting-State Functional Magnetic Resonance Imaging Study
Figure 1
Altered functional network between AE and control. (a) Significant differences between the AE and control groups were found (). For links that showed larger correlation values in the AE group, the corresponding cells of the matrix were set to 1, while smaller correlation values in the AE group resulted in a −1 value for the corresponding cells of the matrix; those cells without a significant difference had a value of 0. (b) A lateral view and (c) a top view of this network are shown. All of the 90 brain regions are marked, and the different colored spheres represent distinct network modules. Notably, the regions are localized according to their centroid stereotaxic coordinates. The edges between the nodes were constructed based on the binarized difference matrix; the red edges indicate that the AE group has a larger functional connectivity than normal, and the blue edges indicate a decreased functional connectivity in the AE group.
