- About this Journal ·
- Abstracting and Indexing ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Recently Accepted Articles ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
BioMed Research International
Volume 2013 (2013), Article ID 734893, 12 pages
Altered Functional Connectivity within and between Brain Modules in Absence Epilepsy: A Resting-State Functional Magnetic Resonance Imaging Study
1Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
2State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, The Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Beijing 100101, China
3University of Chinese Academy of Sciences, Beijing 100039, China
4Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China
Received 28 April 2013; Revised 25 August 2013; Accepted 25 August 2013
Academic Editor: Andrei Surguchov
Copyright © 2013 Cui-Ping Xu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- V. Crunelli and N. Leresche, “Childhood absence epilepsy: genes, channels, neurons and networks,” Nature Reviews Neuroscience, vol. 3, no. 5, pp. 371–382, 2002.
- H. Blumenfeld, “Consciousness and epilepsy: why are patients with absence seizures absent?” Progress in Brain Research, vol. 150, pp. 271–286, 2005.
- L. G. Sadleir, I. E. Scheffer, S. Smith, B. Carstensen, K. Farrell, and M. B. Connolly, “EEG features of absence seizures in idiopathic generalized epilepsy: impact of syndrome, age, and state,” Epilepsia, vol. 50, no. 6, pp. 1572–1578, 2009.
- H. K. M. Meeren, J. P. M. Pijn, E. L. J. M. Van Luijtelaar, A. M. L. Coenen, and F. H. L. da Silva, “Cortical focus drives widespread corticothalamic networks during spontaneous absence seizures in rats,” The Journal of Neuroscience, vol. 22, no. 4, pp. 1480–1495, 2002.
- R. Berman, M. Negishi, M. Vestal et al., “Simultaneous EEG, fMRI, and behavior in typical childhood absence seizures,” Epilepsia, vol. 51, no. 10, pp. 2011–2022, 2010.
- L. E. Betting, S. B. Mory, Í. Lopes-Cendes et al., “MRI volumetry shows increased anterior thalamic volumes in patients with absence seizures,” Epilepsy and Behavior, vol. 8, no. 3, pp. 575–580, 2006.
- L. E. Betting, S. B. Mory, L. M. Li et al., “Voxel-based morphometry in patients with idiopathic generalized epilepsies,” NeuroImage, vol. 32, no. 2, pp. 498–502, 2006.
- R. Caplan, J. Levitt, P. Siddarth et al., “Frontal and temporal volumes in childhood absence epilepsy,” Epilepsia, vol. 50, no. 11, pp. 2466–2472, 2009.
- H. Chahboune, A. M. Mishra, M. N. DeSalvo et al., “DTI abnormalities in anterior corpus callosum of rats with spike-wave epilepsy,” NeuroImage, vol. 47, no. 2, pp. 459–466, 2009.
- C. Luo, Y. Xia, Q. Li et al., “Diffusion and volumetry abnormalities in subcortical nuclei of patients with absence seizures,” Epilepsia, vol. 52, no. 6, pp. 1092–1099, 2011.
- M. C. Y. de Wit, H. M. Schippers, I. F. M. de Coo et al., “Absence epilepsy and periventricular nodular heterotopia,” Seizure, vol. 19, no. 7, pp. 450–452, 2010.
- M. D. Fox and M. E. Raichle, “Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging,” Nature Reviews Neuroscience, vol. 8, no. 9, pp. 700–711, 2007.
- M. Greicius, “Resting-state functional connectivity in neuropsychiatric disorders,” Current Opinion in Neurology, vol. 21, no. 4, pp. 424–430, 2008.
- C. Luo, Q. Li, Y. Lai et al., “Altered functional connectivity in default mode network in absence epilepsy: a resting-state fMRI study,” Human Brain Mapping, vol. 32, no. 3, pp. 438–449, 2011.
- N. Tzourio-Mazoyer, B. Landeau, D. Papathanassiou et al., “Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain,” NeuroImage, vol. 15, no. 1, pp. 273–289, 2002.
- G. Doucet, M. Naveau, L. Petit et al., “Brain activity at rest: a multiscale hierarchical functional organization,” Journal of Neurophysiology, vol. 105, no. 6, pp. 2753–2763, 2011.
- Y. Liu, M. Liang, Y. Zhou et al., “Disrupted small-world networks in schizophrenia,” Brain, vol. 131, no. 4, pp. 945–961, 2008.
- J. Engel Jr., “A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE task force on classification and terminology,” Epilepsia, vol. 42, no. 6, pp. 796–803, 2001.
- Y. Chao-Gan and Z. Yu-Feng:, “DPARSF: a MATLAB toolbox for “pipeline” data analysis of resting-state fMRI,” Frontiers in Systems Neuroscience, vol. 4, no. 13, 2010.
- Y. He, J. Wang, L. Wang et al., “Uncovering intrinsic modular organization of spontaneous brain activity in humans,” PLoS ONE, vol. 4, no. 4, Article ID e5226, 2009.
- A. Lüttjohann, S. Zhang, R. de Peijper, and G. van Luijtelaar, “Electrical stimulation of the epileptic focus in absence epileptic WAG/Rij rats: assessment of local and network excitability,” Neuroscience, vol. 188, pp. 125–134, 2011.
- P. Gloor, “Generalized cortico-reticular epilepsies. Some considerations on the pathophysiology of generalized bilaterally synchronous spike and wave discharge,” Epilepsia, vol. 9, no. 3, pp. 249–263, 1968.
- X. Bai, M. Vestal, R. Berman et al., “Dynamic time course of typical childhood absence seizures: EEG, behavior, and functional magnetic resonance imaging,” The Journal of Neuroscience, vol. 30, no. 17, pp. 5884–5893, 2010.
- G. Van Luijtelaar, E. Sitnikova, and A. Lüttjohann, “On the origin and suddenness of absences in genetic absence models,” Clinical EEG and Neuroscience, vol. 42, no. 2, pp. 83–97, 2011.
- O. Sporns, “The human connectome: a complex network,” Annals of the New York Academy of Sciences, vol. 1224, no. 1, pp. 109–125, 2011.
- D. Fojtiková, M. Brázdil, J. Horký et al., “Magnetic resonance spectroscopy of the thalamus in patients with typical absence epilepsy,” Seizure, vol. 15, no. 7, pp. 533–540, 2006.
- E. A. Tolmacheva, G. Van Luijtelaar, S. A. Chepurnov, Y. Kaminskij, and P. Mareš, “Cortical and limbic excitability in rats with absence epilepsy,” Epilepsy Research, vol. 62, no. 2-3, pp. 189–198, 2004.
- E. Sitnikova and G. van Luijtelaar, “Cortical and thalamic coherence during spike-wave seizures in WAG/Rij rats,” Epilepsy Research, vol. 71, no. 2-3, pp. 159–180, 2006.
- L. M. Birioukova, I. S. Midzyanovskaya, S. Lensu, L. Tuomisto, and G. van Luijtelaar, “Distribution of D1-like and D2-like dopamine receptors in the brain of genetic epileptic WAG/Rij rats,” Epilepsy Research, vol. 63, no. 2, pp. 89–96, 2005.
- M. Boly, C. Phillips, L. Tshibanda et al., “Intrinsic brain activity in altered states of consciousness: how conscious is the default mode of brain function?” Annals of the New York Academy of Sciences, vol. 1129, pp. 119–129, 2008.
- B. J. Baars, “Global workspace theory of consciousness: toward a cognitive neuroscience of human experience,” Progress in Brain Research, vol. 150, pp. 45–53, 2005.
- M. Arthuis, L. Valton, J. Rgis et al., “Impaired consciousness during temporal lobe seizures is related to increased long-distance corticalsubcortical synchronization,” Brain, vol. 132, no. 8, pp. 2091–2101, 2009.
- F. Bartolomei and L. Naccache, “The global workspace (GW) theory of consciousness and epilepsy,” Behavioural Neurology, vol. 24, no. 1, pp. 67–74, 2011.
- P. Boveroux, A. Vanhaudenhuyse, M.-A. Bruno et al., “Breakdown of within- and between-network resting state functional magnetic resonance imaging connectivity during propofol-induced loss of consciousness,” Anesthesiology, vol. 113, no. 5, pp. 1038–1053, 2010.
- E. Hutchinson, D. Pulsipher, K. Dabbs et al., “Children with new-onset epilepsy exhibit diffusion abnormalities in cerebral white matter in the absence of volumetric differences,” Epilepsy Research, vol. 88, no. 2-3, pp. 208–214, 2010.