Suppression of Osteopontin Functions by Levocetirizine, a Histamine Receptor Antagonist, In Vitro
Figure 8
Influence of levocetirizine (LCT) on mRNA expression for GM-CSF, RANTES, and Eotaxin in nasal epithelial cells in vitro. Nasal epithelial cells were stimulated with 250 ng/mL osteopontin (OPN) in the presence of various concentrations of LCT for 12 h. mRNA expression was examined by real-time RT-PCR. *Significant () versus OPN alone; (a) GM-CSF, (b) RANTES, and (c) Eotaxin.