The Sonodynamic Effect of Curcumin on THP-1 Cell-Derived Macrophages

Figure 1

The spectrum of curcumin and the intracellular accumulation of curcumin (×400). Panel A1 is the absorption spectrum of curcumin under a wolfram lamp. panel A2 is the fluorescence emission spectrum of curcumin at 405 nm. Panel B1 is curcumin fluorescence in unfixed macrophages. Panel B2 is nuclei of the same cells after staining with Hoechst 33342. Panel B3 is a merged image of B1 and B2. Scale bar: 20 μm. The dye appeared to be distributed throughout the cells (arrows), and in some cells, it was distributed in the cytoplasm only (arrowhead).