Table 2: Means of renal function during the 24-month observation period ( ).

Renal functionLow-normal BLB groupHigh-normal BLB group (95% CI)
(mL/min/1.73 m2) ( ) ( )

Month 0
 Ccr44.9 ± 10.841.1 ± 12.00.123 (−9.1–1.0)
 D-GFR42.4 ± 6.240.8 ± 7.10.300 (−1.5–4.8)
Month 6( )( )
 Ccr41.5 ± 15.233.1 ± 13.00.010 (−14.6–−2.1)
 D-GFR38.1 ± 9.232.9 ± 8.30.010 (−9.1–−1.3)
Month 12( )( )
 Ccr41.0 ± 19.226.2 ± 12.2<0.001 (−21.6–−8.1)
 D-GFR36.6 ± 9.527.2 ± 8.9<0.001 (−13.6–−5.2)
Month 18( )( )
 Ccr33.1 ± 13.724.5 ± 10.80.003 (−14.1–−3.0)
 D-GFR32.7 ± 11.223.7 ± 8.0<0.001 (−13.3–−4.7)
Month 24( )( )
 Ccr34.2 ± 17.319.8 ± 9.8<0.001 (−20.5–−8.2)
 D-GFR31.4 ± 11.220.2 ± 7.0<0.001 (−15.3–−7.1)
Total decrease of renal function (mL/min/1.73 m2) during the 2-year observation period
 Ccr 12.1 ± 15.5 21.2 ± 8.7 0.002 (3.7–14.5)#
 D-GFR 11.3 ± 11.7 20.5 ± 7.7 0.001 (4.8–13.7)#

Data were measured by the Student's -test except # data by Mann-Whitney method. means significant differences. Ccr: creatinine clearance; D-GFR: estimated GFR for Chinese patients with type II diabetes.