IgE Sensitization to the Nonspecific Lipid-Transfer Protein Ara h 9 and Peanut-Associated Bronchospasm
Table 2
Clinical and IgE parameters of 192 patients with peanut allergy, with or without symptoms of pharyngeal edema.
No symptoms
Hoarse voice
Drooling/dyspnea
Clinical characteristics
Number
112
32
48
% adults
4%
22%
6.3 (1.6–25)*
27%
11.9 (3.2–44)**
% male gender
58%
44%
1.3 (0.5–3.5)
54%
0.7 (0.3–1.6)
AD
79%
59%
0.6 (0.2–1.6)
65%
0.4 (0.2–1.0)
Asthma
54%
55%
1.4 (0.5–3.8)
73%
2.9 (1.2–7.0)*
Rhinitis
24%
50%
3.4 (1.4–8.1)*
60%
4.3 (2.0–9.5)**
Peanut allergen specific IgE
peanut
84%
78%
1.6 (0.4–7.0)
82%
0.6 (0.2–2.7)
Ara h 1
42%
37%
0.6 (0.1–2.4)
35%
1.3 (0.4–4.0)
Ara h 2
65%
57%
0.4 (0.1–1.5)
60%
0.8 (0.2–2.8)
Ara h 3
29%
35%
2.4 (0.8–4.7)
21%
0.7 (0.2–2.2)
Ara h 8
20%
17%
0.7 (0.2–2.5)
19%
0.4 (0.1–1.4)
Ara h 9
17%
12%
0.6 (0.4–1.3)
25%
1.7 (0.5–5.4)
Timothy grass pollen allergen specific IgE
Phl p 1
53%
60%
1.9 (0.5–8.3)
49%
0.5 (0.2–1.6)
Phl p 4
65%
62%
0.5 (0.1–2.2)
68%
1.2 (0.4–3.8)
Phl p 5B
41%
48%
1.5 (0.4–6.1)
47%
2.2 (0.7–6.8)
Phl p 12
54%
65%
0.5 (0.1–2.8)
39%
0.2 (0.1–1.5)
Data are given as percentage of group. Specific IgE ≥ 0.35 kAU/L is defined as “sensitized.” Statistical analysis was performed using multinomial logistic regression analysis quoting Relative Risk (95% confidence interval). * value < 0.05, ** value < 0.005.
