Acetylsalicylic Acid Reduces the Severity of Dextran Sodium Sulfate-Induced Colitis and Increases the Formation of Anti-Inflammatory Lipid Mediators
Figure 5
Effect of 17-HDHA on phagocytosis and overview of DHA-derived lipid mediators. (a) Effect of 17R/S-HDHA on phagocytosis in RAW 264.7 murine macrophages (, *). (b) Synthesis pathways of DHA-derived anti-inflammatory lipid mediators arising from 17R- and 17S-HDHA, and the resulting mediators are called the resolvins D1-4. Included also are the references to the published effects of the DHA-derived mediators on TNF-α secretion from macrophages [23, 48], phagocytosis [56], and DSS-colitis activity [23].
