Fullerenols as a New Therapeutic Approach in Nanomedicine
Figure 2
One-electron redox cycle of anthracyclines. One-electron addition to the quinone moiety in the ring of carbon atoms of DOX and other anthracyclines result in the formation of a semiquinone that quickly regenerates its parent quinone by reducing oxygen to reactive oxygen species (ROS) like and . ROS generated in redox cycle of anthracyclines induce oxidative DNA damage.
