High Glucose-Induced Oxidative Stress Increases the Copy Number of Mitochondrial DNA in Human Mesangial Cells
Figure 3
Effect of MnTBAP on high glucose-induced mtDNA copy number. Synchronized quiescent mesangial cells were incubated with 25 mM glucose in the presence or absence of MnTBAP (200 μM) or 5 mM glucose for 24 h. The copy numbers of ND2 and CYTB per B2M were determined by real-time PCR. Values represent mean ± SD of three independent experiments. compared to 25 mM glucose without MnTBAP.
