- About this Journal ·
- Abstracting and Indexing ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Recently Accepted Articles ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
BioMed Research International
Volume 2013 (2013), Article ID 756209, 8 pages
Frequency and Characteristics of Infections Caused by Extended-Spectrum Beta-Lactamase-Producing Organisms in Neonates: A Prospective Cohort Study
1Department of Paediatrics & Neonatology, PGIMER & Associated Dr. Ram Manohar Lohia Hospital, Baba Kharag Singh Marg, New Delhi 110001, India
2Department of Microbilogy, PGIMER & Associated Dr. Ram Manohar Lohia Hospital, Baba Kharag Singh Marg, New Delhi 110001, India
Received 16 April 2013; Revised 26 July 2013; Accepted 12 August 2013
Academic Editor: Kurt G. Naber
Copyright © 2013 Nandini Vijayakanthi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- U. Chaudhary and R. Aggarwal, “Extended spectrum β-lactamases (ESBL)—an emerging threat to clinical therapeutics,” Indian Journal of Medical Microbiology, vol. 22, no. 2, pp. 75–80, 2004.
- A. Ayyagari and A. Bhargava, “b-lactamases and their clinical significance (A mini review),” Hospital Today, vol. 6, no. 10, pp. 1–6, 2001.
- S. Nathisuwan, D. S. Burgess, and J. S. Lewis II, “Extended-spectrum β-lactamases: epidemiology, detection, and treatment,” Pharmacotherapy, vol. 21, no. 8, pp. 920–928, 2001.
- J. Ena, F. Arjona, C. Martínez-Peinado, M. del mar López-Perezagua, and C. Amador, “Epidemiology of urinary tract infections caused by extended-spectrum beta-lactamase-producing Escherichia coli,” Urology, vol. 68, no. 6, pp. 1169–1174, 2006.
- A. Kaftandzhieva, V. Kotevska, G. Jankoska, B. Kjurcik-Trajkovska, Z. Cekovska, and M. Petrovska, “Extended-spectrum beta-lactamase-producing E. Coli and Klebsiella Pneumoniae in children at University Pediatric Clinic in Skopje,” Macedonian Journal of Medical Sciences, vol. 2, no. 1, pp. 36–41, 2009.
- B. Blomberg, R. Jureen, K. P. Manji et al., “High rate of fatal cases of pediatric septicemia caused by gram-negative bacteria with extended-spectrum beta-lactamases in Dar es Salaam, Tanzania,” Journal of Clinical Microbiology, vol. 43, no. 2, pp. 745–749, 2005.
- G. H. Talbot, J. Bradley, J. E. Edwards Jr., D. Gilbert, M. Scheid, and J. G. Bartlett, “Bad bugs need drugs: an update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America,” Clinical Infectious Diseases, vol. 42, no. 5, pp. 657–668, 2006.
- J. D. Pitout and K. B. Laupland, “Extended-spectrum β-lactamase-producing Enterobacteriaceae: an emerging public-health concern,” The Lancet Infectious Diseases, vol. 8, no. 3, pp. 159–166, 2008.
- F. W. Goldstein, “Antibiotic susceptibility of bacterial strains isolated from patients with community-acquired urinary tract infections in France,” European Journal of Clinical Microbiology and Infectious Diseases, vol. 19, no. 2, pp. 112–117, 2000.
- J. Rodríguez-Baño, M. D. Navarro, L. Romero et al., “Epidemiology and clinical features of infections caused by extended-spectrum beta-lactamase-producing Escherichia coli in nonhospitalized patients,” Journal of Clinical Microbiology, vol. 42, no. 3, pp. 1089–1094, 2004.
- R. Colodner, W. Rock, B. Chazan et al., “Risk factors for the development of extended-spectrum beta-lactamase-producing bacteria in nonhospitalized patients,” European Journal of Clinical Microbiology and Infectious Diseases, vol. 23, no. 3, pp. 163–167, 2004.
- M. Singh, A. Narang, and O. N. Bhakoo, “Predictive perinatal score in the diagnosis of neonatal sepsis,” Journal of Tropical Pediatrics, vol. 40, no. 6, pp. 365–368, 1994.
- V. P. Takkar, O. N. Bhakoo, and A. Narang, “Scoring system for the prediction of early neonatal infections,” Indian Pediatrics, vol. 11, no. 9, pp. 597–600, 1974.
- M. J. Sankar, R. Agarwal, A. K. Deorari, and V. K. Paul, “Sepsis in the newborn,” Indian Journal of Pediatrics, vol. 75, no. 3, pp. 261–266, 2008.
- C. Polinski, “The value of the white blood cell count and differential in the prediction of neonatal sepsis,” Neonatal Network, vol. 15, no. 7, pp. 13–23, 1996.
- O. Da Silva, A. Ohlsson, and C. Kenyon, “Accuracy of leukocyte indices and C-reactive protein for diagnosis of neonatal sepsis: a critical review,” Pediatric Infectious Disease Journal, vol. 14, no. 5, pp. 362–366, 1995.
- H. S. Sader, R. N. Jones, A. C. Gales et al., “Antimicrobial susceptibility patterns for pathogens isolated from patients in Latin American medical centers with a diagnosis of pneumonia: analysis of results from the SENTRY Antimicrobial Surveillance Program (1997),” Diagnostic Microbiology and Infectious Disease, vol. 32, no. 4, pp. 289–301, 1998.
- J. M. Bell, J. D. Turnidge, A. C. Gales, M. A. Pfaller, and R. N. Jones, “Prevalence of extended spectrum β-lactamase (ESBL)-producing clinical isolates in the Asia-Pacific region and South Africa: regional results from SENTRY Antimicrobial Surveillance Program (1998-99),” Diagnostic Microbiology and Infectious Disease, vol. 42, no. 3, pp. 193–198, 2002.
- N. H. Ryoo, E.-C. Kim, S. G. Hong et al., “Dissemination of SHV-12 and CTX-M-type extended-spectrum β-lactamases among clinical isolates of Escherichia coli and Klebsiella pneumoniae and emergence of GES-3 in Korea,” Journal of Antimicrobial Chemotherapy, vol. 56, no. 4, pp. 698–702, 2005.
- X. Jiang, Y. Ni, Y. Jiang et al., “Outbreak of infection caused by Enterobacter cloacae producing the novel VEB-3 beta-lactamase in China,” Journal of Clinical Microbiology, vol. 43, no. 2, pp. 826–831, 2005.
- Y. Hirakata, J. Matsuda, Y. Miyazaki et al., “Regional variation in the prevalence of extended-spectrum β-lactamase-producing clinical isolates in the Asia-Pacific region (SENTRY 1998–2002),” Diagnostic Microbiology and Infectious Disease, vol. 52, no. 4, pp. 323–329, 2005.
- S. Shakil, S. Z. Ali, M. Akram, S. M. Ali, and A. U. Khan, “Risk factors for extended-spectrum β-lactamase producing Escherichia coli and Klebsiella pneumoniae acquisition in a neonatal intensive care unit,” Journal of Tropical Pediatrics, vol. 56, no. 2, pp. 90–96, 2009.
- P. Agrawal, A. Ghosh, S. Kumar, B. Basu, and K. Kapila, “Prevalence of extended-spectrum β-lactamases among Escherichia coli and Klebsiella pneumoniae isolates in a tertiary care hospital,” Indian Journal of Pathology and Microbiology, vol. 51, no. 1, pp. 139–142, 2008.
- P. K. Das, K. Basu, P. Chakraborty, and P. K. Bhowmik, “Clinical and bacteriological profile of neonatal infections in metropolitan city based medical college nursery,” Journal of the Indian Medical Association, vol. 97, no. 1, pp. 3–5, 1999.
- H. Kapoor, M. Sumathi, P. Aggarwal, S. D. Jain, and J. Kaur, “Spectrum of bacterial isolates in high risk areas of a tertiary care hospital: 3 year study,” Indian Journal of Medical Microbiology, vol. 18, pp. 166–169, 2000.
- A. Jain, I. Roy, M. K. Gupta, M. Kumar, and S. K. Agarwal, “Prevalence of extended-spectrum β-lactamase-producing Gram-negative bacteria in septicaemic neonates in a tertiary care hospital,” Journal of Medical Microbiology, vol. 52, no. 5, pp. 421–425, 2003.
- Z. A. Bhutta, “Enterobacter sepsis in the newborn—a growing problem in Karachi,” Journal of Hospital Infection, vol. 34, no. 3, pp. 211–216, 1996.
- H. Abdel-Hady, S. Hawas, M. El-Daker, and R. El-Kady, “Extended-spectrum β-lactamase producing Klebsiella pneumoniae in neonatal intensive care unit,” Journal of Perinatology, vol. 28, no. 10, pp. 685–690, 2008.
- V. C. Cassettari, I. R. da Silveira, M. Dropa et al., “Risk factors for colonisation of newborn infants during an outbreak of extended-spectrum β-lactamase-producing Klebsiella pneumoniae in an intermediate-risk neonatal unit,” Journal of Hospital Infection, vol. 71, no. 4, pp. 340–347, 2009.
- A. Subha, S. Ananthan, and S. V. Alavandi, “Extended spectrum beta lactamase production & multidrug resistance in Klebsiella species isolated from children under five with intestinal & extraintestinal infections,” Indian Journal of Medical Research, vol. 113, pp. 181–185, 2001.
- D. L. Paterson, L. Mulazimoglu, J. M. Casellas et al., “Epidemiology of ciprofloxacin resistance and its relationship, to extended-spectrum β-lactamase production in Klebsiella pneumoniae isolates causing bacteremia,” Clinical Infectious Diseases, vol. 30, no. 3, pp. 473–478, 2000.
- P.-R. Hsueh, R. E. Badal, S. P. Hawser et al., “Epidemiology and antimicrobial susceptibility profiles of aerobic and facultative Gram-negative bacilli isolated from patients with intra-abdominal infections in the Asia-Pacific region: 2008 results from SMART (Study for Monitoring Antimicrobial Resistance Trends),” International Journal of Antimicrobial Agents, vol. 36, no. 5, pp. 408–414, 2010.
- R. Sehgal, R. Gaind, H. Chellani, and P. Agarwal, “Extended-spectrum β lactamase-producing gram-negative bacteria: clinical profile and outcome in a neonatal intensive care unit,” Annals of Tropical Paediatrics, vol. 27, no. 1, pp. 45–54, 2007.
- A. Zapun, C. Contreras-Martel, and T. Vernet, “Penicillin-binding proteins and β-lactam resistance,” FEMS Microbiology Reviews, vol. 32, no. 2, pp. 361–385, 2008.
- Y. Huang, S. Zhuang, and M. Du, “Risk factors of nosocomial infection with extended-spectrum beta-lactamase-producing bacteria in a neonatal intensive care unit in China,” Infection, vol. 35, no. 5, pp. 339–345, 2007.
- A. Asensio, A. Oliver, P. González-Diego et al., “Outbreak of a multiresistant Klebsiella pneumoniae strain in an intensive care unit: antibiotic use as risk factor for colonization and infection,” Clinical Infectious Diseases, vol. 30, no. 1, pp. 55–60, 2000.
- G. Bisson, N. O. Fishman, J. B. Patel, P. H. Edelstein, and E. Lautenbach, “Extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella species: risk factors for colonization and impact of antimicrobial formulary interventions on colonization prevalence,” Infection Control and Hospital Epidemiology, vol. 23, no. 5, pp. 254–260, 2002.
- K. Kristóf, D. Szabó, J. W. Marsh et al., “Extended-spectrum beta-lactamase-producing Klebsiella spp. in a neonatal intensive care unit: risk factors for the infection and the dynamics of the molecular epidemiology,” European Journal of Clinical Microbiology and Infectious Diseases, vol. 26, no. 8, pp. 563–570, 2007.